Brazilian Fever part 1: From patient zero to new HIV

Playthrough of the game Plague Inc, where you play as a disease that needs to wipe out mankind. This is the saga of the Brazilian Fever.


An eight hour bus drive from Mariana, then another two stuck in Sao Paulo’s traffic. Rodrigo felt like a steamroller had ran over him, then backed up again.

Marcelo was waiting for him with a cold beer and a warm kiss. It was nice to be home. How were things over in Mariana? Rodrigo tried to find the right words as he lay collapsed on the couch.

“About as nasty as you’d expect when 40 billion liters of toxic mud from mining refuge leak into Minas Gerais’ main river,” he finally answered. “Towns have no drinking water, all the fish are dead, a roting smell everywhere. Rio Doce is dead for the next century or so and the responsible parties say on TV that all is under control.”

Marcelo touched Rodrigo’s hand, and he felt a sharp twinge of pain.

“Ouch!” Rodrigo yelled.

“Wow, what is that?” Marcelo asked. “Your finger is all red and sore.”

“Must be some bug bite,” Rodrigo said. “You would not believe how many insects the floods stirred up.”

“That’s some nasty bug bite,” Marcelo said. “Does it hurt?”

“Nah, I’m too tired to do anything other than drink beer right now,” Rodrigo said. “I can go back to feeling pain in the morning.”

Patient Zero – 2/12/2015


Patient Zero emerges in Sao Paulo, Brazil, after being infected with a previously unknown virus by an insect bite. He immediately contaminates his roommate when he arrives home in Sao Paulo. There are 7,124,543,961 healthy people in the world.

Silent Night 1 – 24/12/2015


By Christmas eve seven people are infected. The only symptom is constant fatigue. People gather in family reunions and the infections spread by hugs and kisses.

First Mutation – 3/1/2016


The Brazilian Fever virus has mutated and developed the nausea symptom. Thirty three people are infected.

“Irritated stomach lining leads to discomfort. Slight chance of infection when kissing.”

One Thousand Infected – 29/02/2016


“Take your coat, there’s a nasty cold going on.”

In two months, more than one thousand people are infected by the Brazilian Fever Virus, characterized by tiredness and a nausea feeling that doesn’t subside.

Virus travels to Argentina – 04/04/2016


First cases appear outside Brazil, 12 contaminated students from Argentina go back from vacation in Rio de Janeiro. More than 30 thousand people are infected.

The virus develops the Cysts symptom:

“Painful lumps containing pockets of the pathogen. Slight chance of bursting which can spread disease.”

Thousands are infected each day – 15/04/2016


The Brazilian Fever virus goes truly viral. More than 100 thousand are contaminated and thousands are infected every day. The virus has suffered further mutations and now is more easily transmitted by air and water.

“Gives pathogen ability to travel on dust particles. Increase infectivity, especially in arid environments and plane transmission.”

“Pathogen can survive outside the body in fresh, warm water. Increase infectivity, especially in humid environments and ship transmission.”

Australia Infected – 23/04/2016


Cargo boat with contaminated soy arrives in Australia and 8 people are infected. A total of 340 thousand are infected in Brazil.

Drug Resistance – 5/05/2016


“I can stop taking that, I feel better now.”

More than one million people are unknowingly infected with the Brazilian Fever virus. Imperfect treatments leads to the appearance of drug resistant strains.

“Pathogen becomes resistant to class 1 and 2 antivirals. Increases effectiveness in wealthy countries.”

Multiple countries infected – 8/05/2016


More than 1,5 Million are infected in Brazil, and the first infected patients arrive in the United States, Colombia and Peru.

Worse than TB, first cases in Japan and France – 21/05/2016


With close to 10 million infected, the Brazilian Fever virus is more infectious than tuberculosis. 5% of the Brazilian population is contaminated. Four Brazilian workers land in Japan and bring the virus. The first 9 cases appear in France.

50 million infected, Business as usual – 1/6/2016


Almost 60 Million people, more than one quarter of the Brazilian population, are infected with the Brazilian Fever virus. But the disease still is treated as a common cold by the authorities.

Worse than HIV – 5/6/2016


The Brazilian Virus is more infectious than the HIV, close to half the Brazilian population is infected. The disease, however, hasn’t been discovered and is still is treated as a common cold by the authorities.

Stay tuned for part 2: “From discovery to last Christmas”

Guilherme Solari is a Brazilian writer and journalist from Sao Paulo, Brazil. He has written about movies, literature and videogames for some of Brazil’s biggest news sites. He is the author of THE CASCAVEL CHRONICLES, a love letter to 80's action movies, as well as the cyberpunk CYBERSAMPA series.